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Bioreactors I Fermenters

BIOCANVAS ISP Series
Specification

  • Volume

    1000L~100,000L or more

  • Controller

    20inch Touch Screen PLC

  • Sensor

    pH,DO,TEMP,FOAM,ORP,OD ETC.

  • DO CASCASDE, FEED, pH interlock function.

  • Design and manufacture according to ASME-BPE standards.

  • One-stop culture process with the recipe function for each cell.

  • Indirect and direct sterilization sequence user selection function for sterilization control.

  • 21 CFR Part 11 Compliant Digital Chat Recorder SCADA System Remote monitoring and remote control system by application .

  • Sterilization -> Cooling -> Culture -> Transfer -> Storage, etc., automatic control system establishment.
Feature

BIOCANVAS  ISP is a suitable equipment for Pilot scale fermentation and provides a variety of fermentation applications.

Designed for the most optimal culture conditions, it is designed so that anyone can use it without any burden with a fully

automatic system and simple structure that reduces the customer's experimental loss.

The motor drive for stirring can be applied according to the customer's needs in upper and lower ways.

The fermentation tank can be used by conveniently sterilizing the inside of the tank by applying an automatic sterilization

device, and temperature control can also be used uniformly at the set value.

The open frame structure makes valve, piping work and maintenance easy, and various optional devices such as oxygen

supply and gas mix can be applied. And the inside of the fermentation tank can be cleaned more easily when the head lift

system is applied.

The low-speed Top Drive method for cell culture can be used very quietly and stably and The Bottom Drive also applies a

magnet method to achieve quiet and optimal fermentation yield.


●  Apply Intelligent 19" wide touch screen controller.

● Apply PLC SCADA controller system for reliability, stability and easy maintenance suitable for industrial use

● Apply Multi Sensor Board for immediate cause analysis when a problem occurs

● Automatically save setting value, current data, parameter on/off status and PID control to internal memory card and USB.

● Interlocking Control of various biosensors, gas measuring equipment, external pumps and other peripheral devices.

● High-density fermentation Interlocking Control. ( DO-stat, pH-stat, Exponential feeding, etc)

● Apply Auto DO Cascade function.

● Data logging and real-time system remote control using PC software.

● Apply Automatic Top Plate Head Lifting system.

● Easy installation of peripheral devices by applying an integrated frame

● Automatically control flow and mass.

● Stainless pipe transmission line for user's convenience and sterilization system for perfect sterilization.

● Provide the highest level of safety and hermeticity with various nozzles and parts made of precision-machined

● SUS316L material

● cGMP IQ/OQ level fermentation system.

 

 

Specification

 

 

 

Vessel Capacity 

 Total Capacity(L)

 1000L 2000L 3000L 5000L 10,000-100,000L

 Working Volume(L)

 700L 1400L 2100L 3500L 7000L-70,000L

Agitation Control 

 Drive

 AC Motor Top and Bottom drive

(mechanical seal driving)

50~250 ±1 RPM(In the condition of no load)

 Control

 automatic control of agitation speed

 Impellers

 Rushton turbine impeller, Marine impeller , Foam breaker(SUS 316L)

 Sealing

 Mechanical Seal or Magnetic Coupling

 Agitation Type

 Top Drive or Bottom Drive

Head Lift 

  The head lift system is powered by air cylinder motion guide

 Material and

Surface treatment

 Vessel/Piping

 SUS 316L, SUS 304 (electrolytic polishing)

 Sterilization

 Heat exchanger or inject steam into jacket.(105℃~130℃)

 Air Control

 Sparger

 Ring sparger(SUS 316L)

 Filter

 Inlet(0.2㎛), Outlet filter(0.2㎛)

pH Control 

 Range / Electrode

 2.0~14.0 pH of set point, PID control / Gel Type

 DO Control

 Range / Electrode

 0~200% or 0~20ppm, PID control / Polarographic Type

Temp Control 

 Range & Sensor

 Ambient + 3℃~80℃ (0.1℃), RTD(Pt-100), PID control

 Pressure Control

 

 The back pressure is controlled manually and/or automatically

 

 Main Control

 Panel

 17” Touch Screen Color LCD

 Control program

 Process, Trend, Calibration Mode control display.

 all the programmed setting values will be automatically stored into

 the built-in memory.

 Processor

 PLC system

 Setting

 Automated sterilization process

 Automated fermentation program

 Valve control

 Communications

 Memory stick, printer, computer, etc with the RS-232C communication protocol

Data Storage 

 pH, DO, Pressure, Temperature, Anti-Foam and Agitation speed and etc. 

 

 

 

 

 Vessel Ratio (H/D)

 2:1 or Manufactured according to customer requirements

 

 Vessel Surface Treatment

 Inside / outside : 0.6-0.8㎛ / 1.2㎛

 Sight glass : Oblong type

 

Port with Top Plate 

 Exhaust / Port / Pressure Gauge with diaphragm / Pressure Transmitter / Foam Sensor /

Septum Port / Inoculum Port

 Top Port

 Aeration / bypass / Circle Light / Rupture Disk

 Middle Port

 Sampling / pH / DO / Temp / Etc.

 Harvest

 

 

 

 ​ 

Video
Download

  • Industrial Fermenter, Bioreactor Catalog

    2023-02-10

Application